Neurol. pro Praxi, 2002; 3: 149-152

Epilepsie, úzkost a možná paměťový proces: tři vzájemně související fenomény

Georges Chapouthier, Patrice Venault
Hôpital Pitié-Salptrire, Université Paris VI, Francie

Keywords: anxieta, epilepsie, paněť, GABA.

Published: December 31, 2002  Show citation

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Chapouthier G, Venault P. Epilepsie, úzkost a možná paměťový proces: tři vzájemně související fenomény. Neurol. praxi. 2002;3(3):149-152.

Farmakologické látky, jakými jsou na jedné straně agonisté benzodiazepinových receptorů, na druhé straně inverzní agonisté benzodiazepinových receptorů, mají, v závislosti na dávce, tři navzájem související účinky. Jednak jsou účinné při léčbě patologických stavů - epilepsie a úzkostných stavů, kde je jejich efekt připisován, alespoň částečně, ovlivnění komplexu GABA receptorů. Působí také ve fázi učení na paměťový proces, tedy na -normální- mozkovou funkci. Tak epilepsie, anxieta a paměťový proces mohou představovat tři navzájem související fenomény.

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