Neurol. praxi. 2007;8(4):222-225

Pokroky v genetike neurovývojových porúch

prof. MUDr. Ľubomír Lisý, DrSc.
Neurologická klinika SZU a FNsP Bratislava-Ružinov

Vývojové poruchy nervového systému (neurodevelopmental disorders) predstavujú rôznorodú skupinu porúch s viac alebo menej špecifickými príznakmi postihnutia centrálneho nervového systému. Môžu sa tu vyskytovať ADHD, DLD, LD, epilepsia, pervazívne vývojové poruchy, PDD/ASD, Gilles de la Touretteov syndróm, mentálna retardácia, mozgová obrna a poruchy správania (7, 9). Prevalencia niektorých týchto porúch v populácii je uvedená v tabuľke 1.

Keywords: neurovývojové poruchy, pervazívne vývojové poruchy, dyslexia, mikrocefalia, Aspergovo ochorenie, Rettov syndróm, Angelmanov syndróm, schizofrénia, afektívne poruchy

Published: November 1, 2007  Show citation

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Lisý Ľ. Pokroky v genetike neurovývojových porúch. Neurol. praxi. 2007;8(4):222-225.
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    References

    1. Bennett MR, Hacker PMS. Language and cortical function: Conceptual developments. Progres in Neurobiology 2006; 80: 20-52. Go to original source... Go to PubMed...
    2. De Marco P, Merello E, Mascelli S, Capra V. Current perspective on the genetic causes of neural tube defects. Neurogenetics 2006; 7: 201-221. Go to original source... Go to PubMed...
    3. Cohen D, Pichard N, Tordjman S, Baumann C, Burglen L, Excoffier E, Lazar G, Mazet P, Pinquier C, Verloes A, Héron D. Specific genetic disorders and autism: Clinical contribution towards their identification. Journal of Autism and Developmental Disorders 2005; 35: 103-115. Go to original source... Go to PubMed...
    4. Cox J, Jackson AP, Bond J, Woods ChG. What primary microcephaly can tell us about brain growth. Trends in Molecular Medicine 2006; 12: 333-341. Go to original source... Go to PubMed...
    5. Craddock N, Owen MJ. The beginning of the end for the Kraepelian dichotomy. Br J Psychiatry 2005; 186: 364-366. Go to original source... Go to PubMed...
    6. Craddock N, O´Donovan MC, Owen MJ. Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology. Schizophrenia Bulletin 2006; 32: 9-16. Go to original source... Go to PubMed...
    7. Craig AM, Kang Y. Neurexin-neuroligin signaling in synapse development. Current Opinion in Neurobiology 2007; 17: 1-10. Go to original source... Go to PubMed...
    8. Crino PB, Miyata H, Vinters HV.Neurodevelopmental disorders as a cause of seizures: Neuropathologic, genetic, and mechanistic considerations. Brain Pathol 2002; 12: 212-233. Go to original source... Go to PubMed...
    9. Freitag CM. The genetics of autistic disorders and its cliniwcal relevance: a review of the literature. Molecular Psychiatry 2007; 12: 2-22. Go to original source... Go to PubMed...
    10. Grimes DA, Han F Panniset M, Racacho L, Feugxia X, Ruobing Z, Westaff K, Bulman DE.Translated mutation in the Nurr1 gene as a cause for Parkinson´s disease. Mov Disord 2006; 21: 906-909. Go to original source... Go to PubMed...
    11. Gupta AR, State MW. Recent advances in genetics of autism. Biol Psychiatry 2007; 61: 429-437. Go to original source... Go to PubMed...
    12. Jaffee SR. Price TS. Gene-enviroment correlations: a review of the evidence and implications for prevention of mental illness. Molecular psychiatry 2007; 12: 432-442. Go to original source... Go to PubMed...
    13. Kato T. Molecular genetics of bipolar disorder and depression. Psychiatry Clin Neurosci 2007; 61: 3-19. Go to original source... Go to PubMed...
    14. Koukoui SD, Chauhuri A. Neuroanatomical, molecular genetic, and behavioral correlates of fragile X syndrome. Brain Res Rev 2007; 53: 27-38. Go to original source... Go to PubMed...
    15. Krez FK, Dolmetch RE. Molecular mechanisms of autism: a possible role for Ca+ signaling. Current Opinion in Neurobiology 2007; 17: 1-8. Go to original source...
    16. McGrath LM, Smith SD, Pennington BF. Breakthroughs in the search for dyslexia candidate genes. Trends in molecular medicine 2006; 12: 287-342. Go to original source... Go to PubMed...
    17. Mill J, Petronis A. Mollecular studies of major depressive disorder: the epigenetic perspective. Molecular psychiatry 2007; 12: 1-16. Go to original source... Go to PubMed...
    18. Sabaratman M. Fragile-X syndrome. Psychiatry 2006; 5: 325-330. Go to original source...
    19. Swanson JM, Kinsbourne M, Nigg J, Lanphear B, Stefanatos GA, Volkow N, Taylor E, Casez BJ, Castelanos FX, Wadhwa PD. Etiologic subtypes of attention-deficit/hyperactivity disorder: Brain imaging, molecular genetic and environmental factors and dopamine hypothesis. Neuropsychol Rev 2007; 17: 39-59. Go to original source... Go to PubMed...
    20. Williamson SL, Christodoulou j. Rett syndrome: new clinical and molecular insights. Europ. J Human Genet 2006; 14: 896-903. Go to original source... Go to PubMed...

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