Neurol. praxi, 2012; 13(Suppl.E)

Painful and focal diabetic neuropathy

prof.MUDr.Zdeněk Ambler, DrSc.

Neurologická klinika LF UK a FN Plzeň

Painful diabetic neuropathy is common and is associated with significant reduction in quality of life. A distal and symmetric peripheral

neuropathy is the most frequent form, and small fiber damage is thought to result in painful symptoms. The much less common though

well recognized are acute painful and atypical neuropathies. A typical painful neuropathy develops on a background of long-standing

chronic hyperglycemia, associated metabolic derangements, and cardiovascular risk factors in a patient with a chronic, symmetrical,

length-dependent sensorimotor polyneuropathy. Atypical forms are different in several features. They can have an acute or subacute

onset and a monophasic or relapsing course that may develop at any time during a patient’s diabetes mellitus. These are not closely

associated with chronic hyperglycemia or the microvessel abnormalities. Pain may occur in both focal and multifocal forms of diabetic

neuropathy.

Keywords: neuropathic pain, typical and atypical forms of painful neuropathy, focal, multifocal neuropathies

Published: March 1, 2013  Show citation