Neurol. praxi. 2013;14(6):305-308

Sleep disturbances in Parkinson’s disease

MUDr.Petr Dušek, MUDr.Lenka Plchová
Neurologická klinika a Centrum klinických neurověd, Univerzita Karlova v Praze, 1. LF a VFN v Praze

Sleep-Wake disturbances belong to the most common and disabling nonmotor symptoms of Parkinson‘s disease (PD) as they affect 50–95%

patients. Etiology of impaired sleep and wakefulness in PD is multifactorial. Its most important causes are co-existent primary sleep disorders,

medication side effects, overnight re-emergence of motor symptoms, psychiatric comorbidities and primary neurodegeneration of sleep

regulating brain areas itself. To date, very few controlled studies are available to make a recommendation for their management, thus treatment

of sleep-wake disturbances in PD must be tailored individually with respect to presence of comorbidities and patients preferences.

Keywords: Parkinson’s disease, insomnia, excessive daytime sleepiness, sleep apnea, restless legs syndrome, REM sleep behavior disorder

Published: December 1, 2013  Show citation

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Dušek P, Plchová L. Sleep disturbances in Parkinson’s disease. Neurol. praxi. 2013;14(6):305-308.
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