Neurol. praxi. 2022;23(3):249-251 | DOI: 10.36290/neu.2021.037

Autoimmune encephalitis associated with anti-Caspr2 antibodies

MUDr. Martin Sabela1, 2, doc. MUDr. Ondřej Volný, Ph.D.1, 2, doc. MUDr. Michal Bar, Ph.D.1, 2
1 Neurologická klinika, Fakultní nemocnice v Ostravě
2 Lékařská fakulta, Ostravská univerzita

We present a case report of a 61-year-old man with an acute onset of epileptic seizures, encephalopathy, delirium, peripheral nerve hyperexcitability syndrome and dysautonomy with indentified anti-Caspr2 antibodies whose clinical status has promptly improved after a high dose of corticosteroids. Subsequently a short review of anti-Caspr2 pathophysiology, spectrum of clinical manifestation with emphasis put on a typical Morvan syndrome, diagnostics and treatment of these conditions is presented.

Keywords: anti-Caspr2, autoimmune encephalitis, Morvan syndrome.

Received: October 18, 2020; Revised: April 13, 2021; Accepted: May 21, 2021; Prepublished online: May 21, 2021; Published: June 16, 2022  Show citation

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Sabela M, Volný O, Bar M. Autoimmune encephalitis associated with anti-Caspr2 antibodies. Neurol. praxi. 2022;23(3):249-251. doi: 10.36290/neu.2021.037.
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