Neurol. praxi. 2026;27(2):145-150 | DOI: 10.36290/neu.2025.068

From paresthesias to the diagnosis of spinal cord ischemia

MUDr. Natália Cvengrošová1, MUDr. Pavel Potužník, Ph.D.1, MUDr. Ing. Radek Tupý, Ph.D.2
1 Neurologická klinika, Fakultní nemocnice Plzeň a Lékařská fakulta v Plzni, Univerzita Karlova
2 Klinika zobrazovacích metod, Fakultní nemocnice Plzeň a Lékařská fakulta v Plzni, Univerzita Karlova

Paresthesia, as a typical positive sensory symptom, is a common subjectively reported symptom in patients of all age groups. As they can be a manifestation of both central and peripheral nervous system disorders, differential diagnosis is not always straightforward. We describe the case of a young patient, with sudden onset of right-sided hemiparesthesia and objectively mild paresis of the right lower limb, in whom the nature of the difficulties, her young age, the results of imaging and laboratory examinations as well as the information about recent delivery initially led us to consider a possibility of multiple sclerosis. However, further investigation revealed spinal ischemia, a diagnosis that is not only rare and severe but also appears to be underdiagnosed.

Keywords: spinal ischemia, myelopathy, multiple sclerosis, magnetic resonance imaging, paresthesia, intervertebral disc herniation.

Received: July 6, 2025; Revised: September 12, 2025; Accepted: September 18, 2025; Published: April 29, 2026  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Cvengrošová N, Potužník P, Tupý R. From paresthesias to the diagnosis of spinal cord ischemia. Neurol. praxi. 2026;27(2):145-150. doi: 10.36290/neu.2025.068.
Download citation

References

  1. Al-Shaikh RH, Czervionke L, Eidelman B, Dredla BK. Spinal Cord Infarction. PubMed. Published 2023. https://www.ncbi.nlm.nih.gov/books/NBK545185/.
  2. Faig J, Busse O, Salbeck R. Vertebral Body Infarction as a Confirmatory Sign of Spinal Cord Ischemic Stroke. Stroke. 1998;29(1):239-243. doi:https://doi.org/10.1161/01.str.29.1.239. Go to original source... Go to PubMed...
  3. Gofur EM, Singh P. Anatomy, Back, Vertebral Canal Blood Supply. PubMed. Published 2022. https://www.ncbi.nlm.nih.gov/books/NBK541083/.
  4. Jankovic J, Rey Bataillard V, Mercier N, Bonvin C, Michel P. Acute ischemic myelopathy treated with intravenous thrombolysis: Four new cases and literature review. Int J Stroke. 2019 Dec;14(9):893-897. doi: 10.1177/1747493019851289. Epub 2019 May 15. PMID: 31092154. Go to original source... Go to PubMed...
  5. Kobayashi S, Yoshizawa H, Shimada S, Guerrero AR, Miyachi M. Changes of blood flow, oxygen tension, action potential and vascular permeability induced by arterial ischemia or venous congestion on the spinal cord in canine model. Journal of Orthopaedic Research. 2012;31(1):139-146. doi:https://doi.org/10.1002/jor.22197. Go to original source... Go to PubMed...
  6. Kobayashi M. The utility of diffusion-weighted imaging in patients with spinal cord infarction: difference from the findings of neuromyelitis optica spectrum disorder. BMC Neurol. 2022;22(1):382. Published 2022 Oct 11. doi:10.1186/s12883-022-02903-y. Go to original source...
  7. Koeppen BM, Stanton BA. Berne & Levy Physiology. 7th ed. Elsevier; 2018.
  8. Lynch K, Oster J, Apetauerova D, et al. Spinal Cord Stroke: Acute Imaging and Intervention. Case Reports in Neurological Medicine. 2012;2012:1-3. doi:https://doi.org/10.1155/2012/706780. Go to original source... Go to PubMed...
  9. Masson C. Spinal cord infarction: clinical and magnetic resonance imaging findings and short term outcome. Journal of Neurology, Neurosurgery & Psychiatry. 2004;75(10):1431-1435. doi:https://doi.org/10.1136/jnnp.2003.031724. Go to original source... Go to PubMed...
  10. Novy J, Carruzzo A, Maeder P, Bogousslavsky J. Spinal Cord Ischemia. Archives of Neurology. 2006;63(8):1113. doi:https://doi.org/10.1001/archneur.63.8.1113. Go to original source... Go to PubMed...
  11. Pigna F. Spinal cord infarction. A case report and narrative review. Acta bio-medica dell'Ateneo parmense/Acta biomedica. 2021;92(S1):e2021080-e2021080. doi:https://doi.org/10.23750/abm.v92is1.8395. Go to original source... Go to PubMed...
  12. Ros VD, Picchi E, Ferrazzoli V, et al. Spinal vascular lesions: anatomy, imaging techniques and treatment. European Journal of Radiology Open. 2021;8. doi:https://doi.org/10.1016/j.ejro.2021.100369. Go to original source... Go to PubMed...
  13. Štětkářová I. Spinální neurologie. 2. aktualizované a rozšířené vydání. Jessenius. Praha: Maxdorf. 2024; str.235-239. ISBN 978-80-7345-774-7.
  14. Thurnher MM, Bammer R. Diffusion-weighted MR imaging (DWI) in spinal cord ischemia. Neuroradiology. 2006;48(11):795-801. doi:https://doi.org/10.1007/s00234-006-0130-z. Go to original source... Go to PubMed...
  15. Vargas MI, Gariani J, Sztajzel R, et al. Spinal Cord Ischemia: Practical Imaging Tips, Pearls, and Pitfalls. American Journal of Neuroradiology. 2014;36(5):825-830. doi:https://doi.org/10.3174/ajnr.a4118. Go to original source...
  16. Weidauer S, Nichtweiß M, Hattingen E, Berkefeld J. Spinal cord ischemia: aetiology, clinical syndromes and imaging features. Neuroradiology. 2014;57(3):241-257. doi:https://doi.org/10.1007/s00234-014-1464-6. Go to original source...
  17. Wiszniewska M, Sankowska M. Spinal cord ischemia from diagnosis to treatment. Postępy Psychiatrii i Neurologii. 2024;33(2):93-97. doi:https://doi.org/10.5114/ppn.2024.141367 Go to original source... Go to PubMed...
  18. Yadav N, Pendharkar H, Kulkarni GB. Spinal Cord Infarction: Clinical and Radiological Features. Journal of Stroke and Cerebrovascular Diseases. 2018;27(10):2810-2821. doi:https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.06.008. Go to original source... Go to PubMed...
  19. Zalewski NL, Rabinstein AA, Krecke KN, et al. Characteristics of Spontaneous Spinal Cord Infarction and Proposed Diagnostic Criteria. JAMA Neurology. 2019;76(1):56. doi:https://doi.org/10.1001/jamaneurol.2018.2734. Go to original source... Go to PubMed...




Neurology for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.