Neurol. praxi. 2009;10(1):50-53

Classic form of Huntington’s disease manifested by asymmetric Parkinson’s syndrome with rigidity responding to levodopa

MUDr. Věra Zelená, Mgr. Zuzana Fanfrdlová, doc. MUDr. Irena Rektorová, Ph.D.
I. neurologická klinika LF MU a FN u sv. Anny Brno

Huntington’s disease is a hereditary neurodegenerative disease primarily affecting striatal neurons, manifested mostly in adulthood by

a combination of neurological and psychiatric symptoms, most typically by choreatic hyperkinesias and development of dementia. We report

a case of a female patient with Huntington’s disease presenting as multisystem atrophy (MSA) with delayed manifestation of chorea. Unlike

a typical MSA presentation, asymmetry in manifestations of Parkinson’s syndrome and responsiveness to levodopa were evident.

Keywords: Huntington’s disease, Parkinson’s syndrome, „MSA-like” form, rigidity, levodopa

Published: March 1, 2009  Show citation

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Zelená V, Fanfrdlová Z, Rektorová I. Classic form of Huntington’s disease manifested by asymmetric Parkinson’s syndrome with rigidity responding to levodopa. Neurol. praxi. 2009;10(1):50-53.

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